| 產(chǎn)品編號(hào) | IHC0301H |
| 英文名稱 | Human CD14 Ready-To-Use IHC Kit |
| 中文名稱 | 人內(nèi)毒素受體即用型免疫組化試劑盒 |
| 別 名 | CD14; Monocyte differentiation antigen CD14; CD14 molecule; LPS-R; Mo2 |
| 保存條件 | Please store components at the temperatures indicated on the individual tube labels. The kit is stable for 6 months from the date of receipt. |
| 產(chǎn)品介紹 |
CD14 is a 55 kDa GPI-anchored glycoprotein that is constitutively expressed on the surface of mature monocytes, macrophages, and neutrophils. CD14 also serves as a multifunctional lipopolysaccharide receptor, and is released to the serum both as a secreted and enzymatically cleaved GPI-anchored form. CD14 binds lipopolysaccharide molecule in a reaction catalyzed by lipopolysaccharide-binding protein (LBP), an acute phase serum protein. The soluble sCD14 can discriminate slight structural differences between lipopolysaccharides and is important for neutralization of serum allochthonous lipopolysaccharides by reconstituted lipoprotein particles. Further, CD14 has been shown to bind apoptotic cells, and can affect allergic, inflammatory and infectious processes. Alternative splicing results in multiple transcript variants encoding the same CD14 isoform. Diseases associated with CD14 dysfunction include mycobacterium chelonae infection and Croup. |
| 產(chǎn)品圖片 |
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Immunohistochemical analysis of paraffin embedded human endometrial carcinoma tissue slide using IHC0301H (Human CD14 IHC Kit).
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Immunohistochemical analysis of paraffin embedded human colon cancer tissue slide using IHC0301H (Human CD14 IHC Kit).
Immunohistochemical analysis of paraffin embedded human hepatocellular carcinoma tissue slide using IHC0301H (Human CD14 IHC Kit).
Immunohistochemical analysis of paraffin embedded human tonsil tissue slide using IHC0301H (Human CD14 IHC Kit).
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