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LBX1 Rabbit pAb (bs-11867R)  
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產(chǎn)品編號 bs-11867R
英文名稱 LBX1 Rabbit pAb
中文名稱 轉(zhuǎn)錄因子LBX1抗體
別    名 Homeobox; HPX 6; HPX6 antibodyLady bird like homeobox; Ladybird homeobox 1; Ladybird homeobox homolog 1; Ladybird homeobox protein homolog 1; LBX 1; LBX 1H; LBX1H; Transcription factor LBX1; Transcription factor similar to D. melanogaster homeodomain protein lady bird late; LBX1_HUMAN.  
研究領(lǐng)域 細(xì)胞生物  神經(jīng)生物學(xué)  信號轉(zhuǎn)導(dǎo)  干細(xì)胞  轉(zhuǎn)錄調(diào)節(jié)因子  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應(yīng) (predicted: Human,Mouse,Rat,Cow,Zebrafish,Chicken,Dog,Horse)
產(chǎn)品應(yīng)用 WB=1:500-2000,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 30 kDa
檢測分子量
細(xì)胞定位 細(xì)胞核 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human LBX1: 166-250/281 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 The human homolog of the Drosophila lady bird late gene, LBX1, is specifically expressed in the developing central nervous system and musculoskeletal system. The LBX1 gene has a restrictive expression pattern in the dorsal portion of the mantle of the spinal cord and the hindbrain of the CNS. In the developing mouse and chicken musculoskeletal system, Lbx1 is expressed in migrating limb muscle precursor cells. In addition, Lbx1 may regulate migratory patterns of limb muscle cell precursors and may be essential to dorsal identification of forelimb muscles.

Function:
This gene and the orthologous mouse gene were found by their homology to the Drosophila lady bird early and late homeobox genes. In the mouse, this gene is a key regulator of muscle precursor cell migration and is required for the acquisition of dorsal identities of forelimb muscles.

Subunit:
Interacts with SKOR1 which acts as a transcriptional corepressor

Subcellular Location:
Nuclear

Similarity:
Contains 1 homeobox DNA-binding domain.

SWISS:
P52954

Gene ID:
10660

Database links:

Entrez Gene: 10660 Human

Entrez Gene: 16814 Mouse

Entrez Gene: 499362 Rat

Omim: 604255 Human

SwissProt: P52954 Human

SwissProt: P52955 Mouse

SwissProt: Q1XID0 Rat

Unigene: 37128 Human



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