產(chǎn)品編號(hào) | bsm-30211M |
英文名稱 | human CD163 Mouse mAb |
中文名稱 | 人CD163單克隆抗體 |
別 名 | Scavenger receptor cysteine-rich type 1 protein M130; CD 163; CD163 antigen; CD163 molecule; Hemoglobin Scavenger Receptor; M130; M130 antigen precursor; Macrophage associated antigen; MM130; C163A_HUMAN. |
抗體來(lái)源 | Mouse |
克隆類型 | Monoclonal |
克 隆 號(hào) | 3B4 |
交叉反應(yīng) | (predicted: Human) |
產(chǎn)品應(yīng)用 |
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 130 kDa |
檢測(cè)分子量 | 134(non-reduced)/155 |
性 狀 | Liquid |
亞 型 | Mouse IgG1, k |
純化方法 | affinity purified by Protein G |
緩 沖 液 | 0.01M TBS (pH7.4). |
保存條件 | Store at 2-8℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
The protein encoded by this gene is a member of the scavenger receptor cysteine-rich (SRCR) superfamily, and is exclusively expressed in monocytes and macrophages. It functions as an acute phase-regulated receptor involved in the clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages, and may thereby protect tissues from free hemoglobin-mediated oxidative damage. This protein may also function as an innate immune sensor for bacteria and inducer of local inflammation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011] |