| 產(chǎn)品編號(hào) | bs-8662R-BF488 |
| 英文名稱 | Rabbit Anti-BASP1/BF488 Conjugated antibody |
| 中文名稱 | BF488標(biāo)記的腦富含膜附著信號(hào)蛋白1抗體 |
| 別 名 | BASP 1; BASP-1; BASP1 protein; Brain abundant membrane attached signal protein 1; Brain Abundant Signal Protein Membrane Attached 1; Brain Acid Soluble Protein 1; CAP 23; CAP23; MGC8555; NAP 22; NAP-22; NAP22; Neuronal axonal membrane protein NAP 22; Neuronal tissue enriched acidic protein; 22 kDa neuronal tissue enriched acidic protein; BASP1_HUMAN. |
| 規(guī)格價(jià)格 | 100ul/2980元 購(gòu)買 大包裝/詢價(jià) |
| 說(shuō) 明 書 | 100ul |
| 研究領(lǐng)域 | 細(xì)胞生物 神經(jīng)生物學(xué) 表觀遺傳學(xué) |
| 抗體來(lái)源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Human, Mouse, Rat, (predicted: Chicken, Dog, Pig, Cow, Horse, Rabbit, ) |
| 產(chǎn)品應(yīng)用 | ICC=1:50-200 IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 25kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human BASP1/Nap22 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲(chǔ) 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol |
| 保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
background: Neuronal axonal membrane protein Nap-22, also designated neuronal tissue-enriched acidic protein or brain acid soluble protein (BASP1), is a Ca2+-dependent calmodulin-binding protein that is important for neuronal sprouting and plasticity. Nap-22 is abundant in brain nerve terminals and is also present in significant amounts in kidney, testis and lymphoid tissue. Nap-22 undergoes N-terminal myristoylation for membrane localization. It has been characterized as a major protein of neuronal rafts, which are known to preferentially bind membranes containing cholesterol. Nap-22 is a crucial protein active in neurite outgrowth and synaptic plasticity. Function: BASP1 is a brain abundant membrane bound protein with several transient phosphorylation sites and PEST motifs. BASP1 binds calmodulin, is phosphorylated by protein kinase C and undergoes N-terminal myristoylation. BASP1 is expressed specifically in nervous tissue. Intercellular signaling and nerve outgrowth are influenced by a number of proteins expressed at nerve endings and synapses of which BASP1 is one. Subcellular Location: Cell membrane; Lipid-anchor. Cell projection, growth cone. Note=Associated with the membranes of growth cones that form the tips of elongating axons. Tissue Specificity: Brain Similarity: Belongs to the BASP1 family. Database links: Entrez Gene: 10409 Human Entrez Gene: 70350 Mouse Omim: 605940 Human SwissProt: P80723 Human SwissProt: Q91XV3 Mouse Unigene: 201641 Human Unigene: 29586 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
