| 產(chǎn)品編號(hào) |
bs-7356R-PE |
| 英文名稱 |
Rabbit Anti-2 Cys Peroxiredoxin/PE Conjugated antibody
|
| 中文名稱 |
PE標(biāo)記的硫氧還蛋白還原酶抗體 |
| 別 名 |
Antioxidant enzyme;
Peroxiredoxin 1;
Peroxiredoxin 2;
Peroxiredoxin 3;
Peroxiredoxin 4;
Peroxiredoxin 5;
Peroxiredoxin 5 mitochondrial;
PLP;
PMP20;
PRDX1;
PRDX2;
PRDX3;
PRDX4;
PRDX5;
PRX V;
Thioredoxin reductase. |
| 規(guī)格價(jià)格 |
100ul/2980元
購(gòu)買 大包裝/詢價(jià) |
| 說(shuō) 明 書(shū) |
100ul
|
| 研究領(lǐng)域 |
腫瘤 細(xì)胞生物 免疫學(xué) 細(xì)胞凋亡 |
| 抗體來(lái)源 |
Rabbit |
| 克隆類型 |
Polyclonal |
| 交叉反應(yīng) |
Human,
(predicted: Mouse, Rat, Pig, Horse, )
|
| 產(chǎn)品應(yīng)用 |
ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 |
17kDa |
| 性 狀 |
Lyophilized or Liquid |
| 濃 度 |
1mg/ml |
| 免 疫 原 |
KLH conjugated synthetic peptide derived from human 2 Cys Peroxiredoxin |
| 亞 型 |
IgG |
| 純化方法 |
affinity purified by Protein A |
| 儲(chǔ) 存 液 |
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存條件 |
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
background:
Peroxiredoxin (Prx) is a growing peroxidase family whose mammalian members are involved in cell proliferation, differentiation, and apoptosis. There are many isoforms(about 50 proteins), known on the basis of amino acid sequence homology, particularly the amino-terminal region containing an active site cysteine residue. The thiol-specific antioxidant activity is distributed throughout all the kingdoms. Among them, mammalian Prx consists of 6 different members grouped into typical 2 Cys, atypical 2 Cys Prx, and 1 Cys Prx. Except PrxVI belonging to the 1 Cys Prx subgroup, the other five 2 Cys Prx isotypes share the thioredoxin dependent peroxidase(TPx) activity utilizing thioredoxin, thioredoxin reductase, and NADPH as a reducing system. Mammalian Prxs are 20–30 kilodaltons in molecular size and vary in subcellular localization:PrxI, II and VI in cytosol, PrxIII in mitochondria, PrxIV in ER and secretion, PrxV showing complicated distribution including peroxisome, mitochondria and cytosol.
Subcellular Location:
Cytoplasmic.
Database links:
Entrez Gene: 10549 Human
Entrez Gene: 10935 Human
Entrez Gene: 5052 Human
Entrez Gene: 7001 Human
Entrez Gene: 113898 Rat
SwissProt: P30044 Human
SwissProt: P30048 Human
SwissProt: P32119 Human
SwissProt: Q06830 Human
SwissProt: Q13162 Human
SwissProt: Q9R063 Rat
Unigene: 502823 Human
Unigene: 2944 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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